Celebrex (Celecoxib)

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What is Celebrex (Celecoxib)?

Celecoxib is an anti-inflammatory drug (NSAID) that is nonsteroidal. It works by reducing the hormones in the body that cause inflammation as well as pain.

Celecoxib is prescribed to treat inflammation and pain that can be caused by many conditions including arthritis, menstrual pain, and ankylosing spondylitis. It also treats hereditary polyps in the colon.

There are other purposes for this medication that is not listed within this guide.

What is some important information that should be known about Celebrex (Celecoxib)?

A life threatening heart or circulation problem such as heart attack or stroke can occur if this medication is taken long term. Celecoxib cannot be taken before a heart bypass or right after, this includes coronary artery bypass graft, or a CABG.

Medical help should be gotten immediately if you experience weakness, slurred speech, problems with vision or balance, as well as chest pain and shortness of breath.

Serious effects can occur on the intestines or stomach, which include bleeding or perforation of the stomach lining. If this occurs it can be fatal, and it can occur without warning, especially in older adults.

Your doctor should be called if you have symptoms that could show that there is stomach bleeding. Symptoms include bloody, black, or tarry stools, vomiting, or coughing up blood.

Alcohol should not be consumed while taking this celecoxib because it can increase the risk of stomach bleeding.

A doctor or pharmacist should be alerted and asked before any pain medicine, allergy, or cold medicine is taken. Always check labels to make sure you won’t be taking any more NSAIDs, such as ibuprofen, naproxen, aspirin, or ketoprofen.

What should I discuss with my healthcare provider before starting Celebrex (Celecoxib)?

Celecoxib shouldn’t be used before any heart bypass, and it should also not be used after.

This medicine can cause heart or circulation problems that are fatal, such as a heart attack or stroke, especially when used long term.

It can also cause side effects such as stomach or intestines that are serious, including bleeding or perforation, which is the forming of a hole in your stomach. These conditions are most likely fatal and can occur without warning when taking celecoxib. It’s more likely in older adults.

You shouldn’t use this medication when allergic to it or other NSAIDs, including sulfa drugs or aspirin.

Tell your doctor if any of these conditions apply to make sure it is safe to take celecoxib.

  • a bleeding or blood clotting disorder
  • a history of heart attack, stroke, or blood clot
  • a history of stomach ulcers or bleeding
  • a seizure disorder such as epilepsy
  • asthma
  • heart disease, congestive heart failure, high blood pressure
  • liver or kidney disease,
  • polyps in your nose; or

It’s in FDA category D for pregnancy. It’s known that taking this medication in the last three months of pregnancy can pose a risk to the unborn child. You should always tell your doctor if you’re pregnant or plan to become pregnant while you take celecoxib.

It’s known to pass into breast milk. This means it can affect any nursing child. Do not take it without first talking to your doctor if you’re already breast feeding a child.

This medication should not be given to anyone under two years of age unless otherwise prescribed by a doctor.

Side Effects of Celebrex

Emergency medical help is needed if any of these signs of an allergic reaction occur: hives, swelling of your face, tongue, throat or lips, as well as difficulty breathing.

Stop taking celecoxib as well as call your doctor if these side effects occur. They include: urinating less than usual or not at all

  • swelling or rapid weight gain
  • skin rash, bruising, severe tingling, numbness, pain, muscle weakness; or
  • severe skin reaction — fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, turning into a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
  • coughing up blood or vomit that looks like coffee grounds
  • chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance
  • black, bloody, or tarry stools

Less serious side effects:

  • dizziness, nervousness, headache
  • mild skin rash
  • runny or stuffy nose, sore throat; or
  • upset stomach, diarrhea, bloating, gas

A complete list of side effects is not in this document, and other side effects may occur. Call your doctor for medical advice for a more detailed list. Side effects should be reported to the FDA at 1-800-FDA-1088.

Celebrex Interactions

Before using an antidepressant, such as citalopram (Celexa), fluoxetine (Prozac, Sarafem, Symbyax), escitalopram (Lexapro), fluvoxamine (Luvox), sertraline (Zoloft), or paroxetine (Paxil), make sure that you ask your doctor. Any of these medications if taken with a NSAID can cause bruising or easy bleeding.

Discuss with your doctor all other medicines you use, especially:

  • lithium (Eskalith, Lithobid)
  • fluconazole (Diflucan)
  • an ACE inhibitor such as benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others
  • heart or blood pressure medication such as candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro, Avalide), losartan (Cozaar, Hyzaar), valsartan (Diovan), telmisartan (Micardis), or olmesartan (Benicar); or
  • diuretic (water pill) like furosemide (Lasix)
  • blood thinner like warfarin (Coumadin, Jantoven)

The list provided is not complete because other drugs may interact with celecoxib, so always tell your doctor about any medications you’re taking. This includes prescription drugs as well over-the-counter, vitamin, and herbal products. Don’t start a new medication without telling your doctor before adding into your routine.

What should be avoided when taking Celebrex (Celecoxib)?

You should avoid drinking any alcohol while taking this drug. The risk of stomach bleeding could be increased with alcohol consumption.

Don’t take celecoxib wih other NSAID, including ibuprofen (Motrin, Advil), Cataflam, naproxen (Aleve, Naprosyn, Naprelan, Treximet), diclofenac (Arthrotec, Cambia, Voltaren, Flector Patch, Pennsaid, Solareze), diflunisal (Dolobid), etodolac (Lodine), mefenamic acid (Ponstel), nabumetone (Relafen), flurbiprofen (Ansaid), indomethacin (Indocin), ketorolac (Toradol), meloxicam (Mobic), ketoprofen (Orudis), or piroxicam (Feldene).

If you need to use any other cold, pain medication, or allergy medication, you should ask your doctor or pharmacist before adding it to your medications.

Before using any other cold, allergy, or pain medicine you need to ask a pharmacist or your doctor. Medicines similar to celecoxib are contained in many combination medicines, and therefore taking some of them together can cause you to get too much of a certain type of drug, causing health issues. Always check the label to see if a medicine contains any sort of NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen, aspirin, ketoprofen, or naproxen.

Sunlight or tanning beds are to be avoided when taking celecoxib because it can make you sunburn much more easily. Always wear protective clothing as well as sunscreen, usually with an SPF of 30 or higher.

Celebrex Dosage

Always take the exact prescription that your doctor has prescribed. Larger or smaller amounts or for longer than recommended can be a danger. Always follow the directions printed on the prescription label.

Taking this medication with milk or food will cut down on stomach upset.

To make swallowing easier, feel free to open the capsule and sprinkle celecoxib into a spoonful of applesauce. Don’t chew, but instead swallow immediately. The empty capsule should then be discarded, and if you don’t want to take it right away keep it refrigerated.

If this medication is to be used long-term, blood tests should be frequent. So remember to see your doctor regularly.

It should be stored away from both moisture and heat, as well as room temperature.

What will happen if I overdose on Celebrex (Celecoxib)?

You should seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if you or someone you know has experienced an overdose.

Overdose symptoms on Celebrex can include vomiting, nausea, coughing up blood, drowsiness, stomach pain, black or bloody stools, shallow breathing, fainting, or coma.

What happens if a dose of Celebrex (Celecoxib) is missed?

Celecoxib is a medication that is taken as needed, so there is most likely no dosing schedule. If the medication is being taken regularly, the missed dose should be taken as soon as you remember. Only skip the dose if it is near the time your next one is scheduled. Extra medication just because you missed a dose is harmful.

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